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(A-B) miR-27a-3p mimic significantly increased SW480 cell migration by scratch wound healing assay (A) and cell migration assay (B), respectively. (C) miR-27a-3p mimic significantly increased SW480 cell invasion compared with the control group. (D-E) miR-27a-3p inhibitor significantly suppressed HCT116 cell migration (D) and invasion (E). However, RXRα knockdown reversed suppression of cell migration (D) and invasion (E) in HCT116 induced by miR-27a-3p inhibitor.
