Table 3. Post-treatment echocardiographic data.

Variables	Sham (n=15)	AS (n=13)	AS-GH (n=08)
BW (g)	484 ± 42	415 ± 31*	476 ± 58#
LVDD (mm)	7.73 ± 0.53	7.93 ± 1.42	7.98 ± 1.02
LVDD/BW (mm/kg)	15.54 ± 1.45	18.47 ± 3.20*	16.53 ± 3.62#
LVSD (mm)	3.16 ± 0.51	4.08 ± 1.74	3.20 ± 0.91
PWDT (mm)	1.43 ± 0.09	2.25 ± 0.25*	2.41 ± 0.37*
PWST (mm)	3.03 ± 0.21	3.79 ± 0.48*	4.33 ± 0.63*
IVSST (mm)	2.80 ± 0.19	3.05 ± 0.26*	3.44 ± 0.30*#
IVSDT (mm)	1.45 ± 0.08	2.26 ± 0.24*	2.40 ± 0.35*
AO (mm)	3.9 ± 0.1	4.1 ± 0.2*	4.0 ± 0.2
LA (mm)	4.9 ± 0.2	7.0 ± 0.8*	7.8 ± 1.2*
LA/AO	1.28 ± 0.06	1.74 ± 0.19*	1.92 ± 0.30*
LA/BW (mm/kg)	9.89 ± 0.79	16.22 ± 1.68*	15.87 ± 2.08*
LVRWT	0.37 ± 0.03	0.58 ± 0.10*	0.62 ± 0.16*
HR (bpm)	303 ± 43	298 ± 27	308 ± 21
EFS (%)	59.1 ± 5.6	49.8 ± 14.7*	59.8 ± 12.1#
MWFS (%)	32.8 ± 3.2	26.6 ± 7.9*	31.6 ± 6.3
LVEF	0.93 ± 0.03	0.87 ± 0.10	0.92 ± 0.08
PWSV (mm/s)	38.6 ± 7.2	25.2 ± 5.1*	25.6 ± 3.1*
E-wave	74 ± 8.5	132 ± 15.7*	121 ± 19.0*
A-wave	55 ± 15.9	26 ± 5.0*	23 ± 5.8*
E/A	1.45 ± 0.37	5.23 ± 0.97*	5.59 ± 1.31*
EDT (ms)	53 ± 4.3	33 ± 4.8*	29 ± 5.9*
IVRT (ms)	33 ± 4.18	24 ± 4.70*	21 ± 5.77*
IVRTn (ms)	34 ± 4.3	23 ± 5.0*	21 ± 5.5*

Data are expressed as mean ± standard deviation. AS: aortic stenosis; AS-GH: aortic stenosis treated with growth hormone; n: number of animals; ; LVDD and LVSD: left ventricle (LV) diastolic and systolic diameters, respectively; PWDT and PWST: LV posterior wall diastolic and systolic thicknesses, respectively; IVSST and IVSDT: interventricular septum systolic and diastolic thicknesses, respectively; AO: aortic diameter; LA: left atrial diameter; LVRWT: LV relative wall thickness; HR: heart rate (beats/min); EFS: endocardial fractional shortening; MWFS: midwall fractional shortening; LVEF: LV ejection fraction; PWSV: LV posterior wall shortening velocity; E/A: early-to-late diastolic mitral inflow ratio; EDT: E-wave deceleration time; IVRT: isovolumetric relaxation time; IVRTn: IVRT normalized to heart rate. ANOVA and Tukey; * p<0.05 vs Sham; # p<0.05 vs AS.