Table 4. Protein expression.
Proteins (arbitrary units) |
Sham (n=08) |
AS (n=08) |
AS-GH (n=07) |
---|---|---|---|
MyoD | 1.04 (0.88-1.13) | 1.10 (0.90-1.42) | 1.47 (1.11-1.79) |
Myogenin | 1.00 ± 0.38 | 0.58 ± 0.36 | 0.87 ± 0.68 |
MRF4 | 0.88 (0.62-1.35) | 0.60 (0.34-1.19) | 1.33 (0.79-3.27) |
Akt | 1.00 ± 0.54 | 0.86 ± 0.35 | 0.86 ± 0.54 |
Atrogin-1 | 1.00 ± 0.44 | 0.73 ± 0.19 | 0.92 ± 0.18 |
MuRF-1 | 1.00 ± 0.90 | 0.53 ± 0.41 | 0.63 ± 0.23 |
Myostatin | 1.00 ± 0.32 | 1.86 ± 1.09 | 2.05 ± 1.07 |
Follistatin | 1.00 ± 1.11 | 1.42 ± 0.83 | 1.31 ± 1.44 |
Pax-7 | 1.00 ± 0.39 | 1.06 ± 0.63 | 0.74 ± 0.63 |
Data are expressed as mean ± standard deviation or median and percentiles. AS: aortic stenosis; AS-GH: aortic stenosis treated with growth hormone; n: number of animals. ANOVA and Tukey or Kruskal-Wallis and Student-Newman-Keuls; p>0.05 for all proteins.