Table 3. Univariate and multivariate Cox proportional hazards regression model analysis of factors for OS in patients with CRC in validation cohort.
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95%CI | P value | |
| Gender | 1.023 | 0.609-2.027 | 0.694 | |||
| Age | 1.508 | 0.732-2.893 | 0.192 | |||
| Tumor size | 1.667 | 0.545-2.831 | 0.220 | |||
| Differentiation | 1.891 | 1.034-3.257 | 0.077 | |||
| Local invasion | 1.548 | 0.948-2.769 | 0.144 | |||
| Distant metastasis | 2.625 | 1.577-3.836 | 0.010 | 2.701 | 1.495-4.432 | 0.008 |
| TNM stage | 2.257 | 1.144-3.506 | 0.037 | 2.209 | 1.112-3.417 | 0.043 |
| Serum XIST level | 1.927 | 0.381-2.234 | 0.005 | 1.990 | 0.378-2419 | 0.007 |