Table 2. Structural groups of progestogens and the year of development.
| Structurel Groups | Progestogen | Year of synthetization and/or market introduction |
|
|---|---|---|---|
| Progesterone | Progesterone | 1933/1997 | |
| Retroprogesterone | Dydrogesterone | 1959 | |
| Progesterone Derivate | Medrogestone | 1964 | |
| 17a-Hydroxyprogesterone Derivates | Pregnanes (C21) | Medroxyprogesterone acetate | 1957 |
| Megestrol | 1959 | ||
| Chlormadinone acetate | 1959 | ||
| Cyproteroneacetate | 1961 | ||
| 17a-Hydroxynorprogesterone Derivates | Norpregnanes (C20) | Nomegestrol acetate | 1986 |
| Gestenoron Caproate | 1973 | ||
| 19-Norprogesterone Derivates | Norpregnanes (C19) | Demegestone | 1974 |
| Promegestone | 1983 | ||
| Nestorone | 2001 | ||
| Trimegestone | 2001 | ||
| 19-Nortestosterone Derivates | Estranes (C18) | Norethindrone | 1951 |
| Norethisterone acetate | 1951 | ||
| Lynestrenol | 1961 | ||
| Norethinodrel | 1957 | ||
| Ethynodiol Acetat | 1967 | ||
| 19-Nortestosterone Derivates | Gonanes (C17) | Norgestrel | 1966 |
| Levonorgestrel | 1966 | ||
| Desogestrel | 1981 | ||
| Etonogestrel | 1998 | ||
| Gestoden | 1986 | ||
| Norgestimate | 1986 | ||
| Dienogest | 1978 | ||
| Spirolonactone Derivate | Drospirenone | 1976 |