Table 3.

Predicted infliximab trough concentrations at steady-state in children with Crohn's Disease by dosing strategy (n=34).

	Infliximab Maintenance Dosing Regimen
	5 mg/kg			7.5 mg/kg			10 mg/kg
	q 8 wk	q 6 wk	q 4 wk	q 8 wk	q 6 wk	q 4 wk	q 8 wk	q 6 wk	q 4 wk
Trough, ug/ml median (IQR)	2.2 (1.2-3.4)	4.8 (3.0-7.1)	11.5 (8.4-15.6)	3.3 (1.8-5.1)	7.2 (4.5-10.6)	17.3 (12.7-23.4)	4.4 (2.4-6.8)	9.5 (6.0-14.2)	23.0 (16.9-31.2)
% >3 ug/ml	32	74	94	62	79	94	71	82	94
% >5 ug/ml	6	47	82	26	74	94	38	76	94

Dosing interval expressed in weeks (wk). Trough concentrations were predicted at the end of the dosing interval for a given strategy.