Table 1.

Change in biomarker plasma concentrations.

	Metformin (N = 35)	Placebo (N = 42)	p-value
Total cholesterol	12.6 (−114 to 175)	17.1 (−294 to 143)	0.762
High-density lipoproteins	−2.3 (−25 to 39)	−7.5 (−40 to 14)	0.019
Oxidized low-density lipoproteins	−12.2 (−70 to 33)	−3.8 (−53 to 71)	0.038
Glucose	−9.2 (−85 to 58)	−4.2 (−50 to 33)	0.847
Insulin	1.8 (−850 to 1,382)	−100.2 (−910 to 343)	0.075
Unacylated Ghrelin	50.6 (−156 to 1,437)	51.8 (−202 to 650)	0.299
Leptin	12.4 (−17 to 33)	9.25 (−14 to 83)	0.339

Data presented as median (range).