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. 2017 Nov 3;7:14472. doi: 10.1038/s41598-017-15196-w

Figure 5.

Figure 5

Perinatal exposure to BPA impairs local IgA production and antimicrobial activity leading to dysbiosis in faeces. (a) Faecal IgA and polyIgR levels were assessed and a linear regression has been made to correlate these two parameters in BPA and vehicle exposed offspring at PND45 and PND170. (b) Impact of 1 mg of faecal supernatant protein on commensal E. coli growth and lysozyme activity in faecal supernatant from BPA and vehicle exposed offspring at PND45 and PND170. Data represent the mean ± s.e.m. (n = 8–16). Data were representative from two batches of experiments. *P < 0.05, **P < 0.01, ***P < 0.001 vs. non-exposed group using a Mann-Whitney’s post-hoc analysis.