Table 1.
Results of ocular coherent tomography (OCT) in patients with Wilson’s disease with neurological symptoms Unified Wilson’s Disease Rating Scale (UWDRS+) and those without neurological feature (UWDRS−)
| Parameter | UWDRS+ (N = 30) | UWDRS− (N = 28) | p value | Difference | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| RNFL (µm) | 88.05 | 8.39 | 94.76 | 7.43 | 0.002 | −6.71 |
| Retinal nerve fiber layer measurements | ||||||
| S | 110.00 | 10.84 | 115.13 | 13.01 | 0.082 | − |
| T | 61.74 | 9.38 | 69.65 | 10.42 | 0.005 | −7.91 |
| I | 115.20 | 12.07 | 120.81 | 11.16 | 0.082 | – |
| N | 70.41 | 8.97 | 74.17 | 10.43 | 0.162 | – |
| Macular thickness measurements | ||||||
| Mth (µm) | 254.46 | 16.39 | 268.35 | 19.76 | 0.007 | −13.89 |
| GCIP | 78.59 | 3.26 | 81.93 | 3.59 | 0.001 | −3.34 |
| INL | 32.81 | 2.28 | 35.89 | 2.51 | >0.000 | −3.08 |
| OPL | 30.70 | 1.30 | 30.85 | 1.43 | 0.693 | – |
| ONL + PRL | 118.91 | 3.84 | 11,989 | 4.73 | 0.406 | – |
GCIP ganglion cell and inner plexiform layer, I inferior part, INL inner nuclear layer, Mth total macular thickness, N nasal part, ONL + PRL outer nuclear layer and photoreceptor layer, OPL outer plexiform layer, RNFL retinal nerve fiber layer, S superior part, SD standard deviation, T temporal part