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. 2017 Nov 3;7:14491. doi: 10.1038/s41598-017-14967-9

Table 5.

Differentially expressed genes that were involved in the immune system and endocrine system.

Pathway Gene_Symbol Gene_Name FPKM log 2 FoldChange FDR
SAT VAT TAT SAT/VAT SAT/TAT VAT/TAT SAT/VAT SAT/TAT VAT/TAT
PPAR signaling pathway
RXRA Retinoid X receptor, alpha 23.710 13.230 28.251 1.381 0.013
DBI Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1294.623 808.037 1827.389 1.471 0.006
SLC27A6 Solute carrier family 27 (fatty acid transporter), member 6 3.832 1.117 2.073 1.814 0.013
Adipocytokine signaling pathway
PPARGC1A Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.557 0.619 0.063 2.929 0.033
AKT2 V-akt murine thymoma viral oncogene homolog 2 111.075 76.556 142.164 1.200 0.043
TNFRSF1B Tumor necrosis factor receptor superfamily, member 1B 15.132 22.681 6.001 1.624 0.003
CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1, alpha 9.824 4.345 14.618 2.050 0.000
Insulin signaling pathway
SREBF1 Sterol regulatory element binding transcription factor 1 94.887 56.989 130.733 1.523 0.028
PIK3R5 Phosphoinositide-3-kinase, regulatory subunit 5 2.010 2.684 0.766 1.512 0.033
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.712 2.622 11.250 2.297 2.420 0.000 0.000
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 4.834 2.656 1.445 1.512 0.034
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 3.659 6.384 1.011 1.568 2.355 0.025 0.000
Insulin secretion
LOC105606031 Adenylate cyclase type 5-like 0.510 0.317 0.956 1.858 0.012
KCNN3 Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.638 3.977 0.576 2.469 0.000
ADCYAP1R1 Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.570 0.428 0.467 2.653 0.035
CREB5 cAMP responsive element binding protein 5 7.442 13.803 3.418 1.704 0.006
CREB3L2 cAMP responsive element binding protein 3-like 2 9.003 8.142 2.493 1.597 1.429 0.019 0.032
ADCY7 Adenylate cyclase 7 2.597 3.874 1.084 1.533 0.015
ADCY5 Adenylate cyclase 5 8.749 8.025 22.870 1.603 1.778 0.008 0.000