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. 2017 Nov 3;7:14481. doi: 10.1038/s41598-017-14976-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Radiofrequency response of nCP:Fe and its effect on cell viability. (A) Impedance spectroscopy analysis showing variation of tan δ value of nCP:Fe with frequency (B) Schematic of non-invasive RF system (C) Change in temperature obtained by RF exposure of different concentration of nanoparticles at 100 W for 1 minute. (D) Viability of nCP:Fe/nCP treated N1S1 hepatoma cells, 4 hours after RF treatment (100 W power was applied for 5 minutes). Viability test was done 48 hours after RF exposure. Optical microscope images of (E) untreated (F) nCP:Fe treated cells, 48 hours after RF exposure.