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. 2017 Oct 30;8:1419. doi: 10.3389/fimmu.2017.01419

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Copyright © 2017 Minoda, Virshup, Leal Rojas, Haigh, Wong, Miles, Wells and Radford.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of chemokines CXCL9 and CXCL10 by hu mouse CD141⁺ dendritic cells (DC) and CD1c⁺ DC. (A) Normalized log 2 expression of CD1c⁺ DC and CD141⁺ DC genes following 2 h activation with poly I:C and/or R848 in vivo in hu mice. Boxes represent 25th–75th percentiles ± minimum and maximum values with line at the median from DC sorted from 2 to 3 individual mice (B) Chemokine protein levels in the serum of hu mice 2 h after activation. (C) Production of chemokine protein by purified hu mouse DC 18 h after activation in vitro, versus control [cultured in medium alone in vitro (cont)].