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Hypothalamic LN229 glioblastoma cells implantation. (A) An example of a coronal slice of brain tissue where implanted cells resulted in tumor masses compromising hypothalamic, ventricular and optic tract structures. (B) Another example showing a brain where the tumor affected the ipsilateral SCN and the optic chiasm. (C) Tumor implantation resulted in vascularization of the tissue (yellow arrows). OC, Optic chiasm; 3V, third ventricle.
