. 2017 Oct 30;8:301. doi: 10.3389/fendo.2017.00301

Table 3.

Percentage of pregnancies with normal, small, or adverse litters in dams treated with OFS, S, both, or neither.

	Lean-Control	Obese-HFS	Obese-Control	Obese-OFS	Obese-S	Obese-OFS + S
Normal litter	50	0	50	44	18	0
Small litter	20^ab	45^ab	0^a	12^ab	64^b	67^ab
Adverse	30	55	50	44	18	33

Values are presented as mean percentage of all pregnancies resulting in normal, small, or adverse litter status (n = 9 for Obese-OFS and Obese-OFS + S; n = 10 for Lean-Control and Obese-Control; n = 11 for Obese-HFS and Obese-S).

HFS, high fat/sucrose; OFS, oligofructose; S, sitagliptin.

Obese in the group name indicates diet-induced obese rats that underwent the respective prepregnancy interventions, except Obese-HFS that remained untreated and consumed HFS diet throughout the study. Lean in the group name indicates a lean reference group that never underwent the obesity induction period and consumed control AIN-93 diet throughout the study. Mean values with different superscripts are significantly different between treatment groups (p < 0.05).