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. 2017 Nov 3;18:185. doi: 10.1186/s12931-017-0668-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Collagen fibre content in alveolar septa (a) and pulmonary vessel wall (b). Representative photomicrographs of alveolar septa (c) and pulmonary vessels (d), stained with the Picrosirius-polarization method. Note the enlargement of alveolar space in the ELA-Sal group. C: control; ELA: elastase-induced emphysema; Sal: i.p. injection of saline; Ghr: i.p. injection of ghrelin. Boxes show the interquartile range (25^th–75^th percentile), whiskers encompass the range (minimum–maximum), and horizontal lines represent the median in 10 animals/group. * vs. C-Sal. # vs. ELA-Sal