Table 2.

Semi-quantitative analysis of electron microscopy

	C		ELA
	Sal	Ghr	Sal	Ghr
Type 2 epithelial cell damage	0 [0-1]	1 [0-1]	3 [2.5-3.5]*	2 [2-3]
Endothelial cell damage	1 [0-1]	0 [0-0.5]	3 [3-3.5]*	2 [1.5-2.5]#
Collagen fibre	0 [0-0.5]	0 [0-0.5]	3 [2.5-3.5]*	2 [1-2]#
Activated macrophage	0 [0-1]	1 [0-1]	2 [1.5-2]	3 [2.5-3.5]*#

Values are median [interquartile range] of 5 animals per group. C control, ELA elastase-induced emphysema, Sal i.p. injection of saline, Ghr i.p. injection of ghrelin. Pathologic findings were graded on a five-point, semi-quantitative, severity-based scoring system, where 0 = normal lung parenchyma, 1 = changes in 1–25% of examined tissue, 2 = 26–50% of examined tissue, 3 = 51–75% of examined tissue, and 4 = 76–100% of examined tissue. * vs. C-Sal. # vs. ELA-Sal