Table 2.

Differences between direct measurement of LDL-C and calculation, sensitivity and specificity (using an LDL-C cut-off of 100 mg/dL) in different TG levels

TG	LDL-C	N	Mean(SD)	Z (P-value)	r (P-value)	Sensitivity	Specificity
<50(mg/dL)	Direct (mg/dL)	41	66.4 (14.5)
	Friedwald(mg/dL)	41	73.2(20.1)	−4.5 (<0.001)	0.96 (<0.001)	100.0	92.5
	Anandraja(mg/dL)	41	86.4 (24.8)	−5.5 (<0.001)	0.86 (<0.001)	100.0	77.5
	Chen(mg/dL)	41	69.4 (18.2)	−3.0 (0.003)	0.96 (0.002)	100.0	97.5
51–150 (mg/dL)	Direct (mg/dL)	983	79.3(21.3)
	Friedwald(mg/dL)	983	84.3 (28.2)	−16.1 (<0.001)	0.98 (<0.001)	100.0	89.3
	Anandraja(mg/dL)	983	89.9 (29.5)	−21.8 (<0.001)	0.94 (<0.001)	98.7	80.7
	Chen(mg/dL)	983	84.2 (25.6)	−20.7 (<0.001)	0.98 (<0.001)	100.0	91.3
151–300 (mg/dL)	Direct (mg/dL)	597	92.7(25.3)
	Friedwald(mg/dL)	597	90.6(34.6)	−5.2 (<0.001)	0.98 (<0.001)	90.0	94.8
	Anandraja(mg/dL)	597	91.2 (34.9)	−35.0 (<0.001)	0.96 (<0.001)	92.4	92.2
	Chen(mg/dL)	597	97.7 (31.5)	−13.6 (<0.001)	0.99 (<0.001)	99.0	88.4
301–400 (mg/dL)	Direct (mg/dL)	70	104.1(27.6)
	Friedwald(mg/dL)	70	94.0 (41.3)	−4.7 (<0.001)	0.98 (<0.001)	83.3	100.0
	Anandraja(mg/dL)	70	90.4 (42.5)	−5.6 (<0.001)	0.98 (<0.001)	65.0	100.0
	Chen(mg/dL)	70	111.9 (37.1)	−4.9 (<0.001)	0.95 (<0.001)	100.0	91.2
401–500 (mg/dL)	Direct (mg/dL)	21	118.6 (31.3)
	Friedwald(mg/dL)	21	107.8(49.8)	−1.9 (<0.001)	0.99 (<0.001)	92.9	100.0
	Anandraja(mg/dL)	21	104.9(50.8)	−2.3 (0.02)	0.98 (0.007)	92.9	100.0
	Chen(mg/dL)	21	131.6(45.1)	−2.9 (<0.003)	0.99 (<0.001)	100.0	100.0
501–1000 (mg/dL)	Direct (mg/dL)	9	113.4(26.8)
	Friedwald(mg/dL)	9	72. 9(50.1)	−2.0 (0.038)	0.51 (0.02)	28.6	100.0
	Anandraja(mg/dL)	9	69.9(46.2)	−2.4 (0.02)	0.58 (<0.008)	28.6	100.0
	Chen(mg/dL)	9	121.0(44.2)	−0.59 (0.55)	0.64 (<0.50)	71.4	100.0