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. 2017 Nov 3;14:43. doi: 10.1186/s12989-017-0224-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Stimulation of 16HBE cells with ATP potentiates a subsequent activation of TRPV4. a, b Effects of the TRPV4 agonist GSK1016790A on the [Ca²⁺]_i of HEK293T cells transfected with mouse TRPV4, in control (a, n = 253) or after extracellular perfusion of ATP (b, n = 266). The thick continuous traces correspond to the average responses and the thin dashed traces correspond to the mean plus/minus the standard errors