The results of the analysis combining LRS and other different pCR predictors performed for the whole group of patients. In order to inspect the clinical significance of LRS, we combined LRS with other factors which may be related to pCR. Age (A), ER status (B), HER2 status (C), tumor size (D), lymph node metastasis status (E), tumor grade (F), Gene21 index (G), Gene70 index (H), and GGI (I) which were available in our cohort were integrated, respectively, with LRS and divided patients into four groups. The pCR rates were compared among each of the four groups.