Table 1.

NAC Patients' Clinicopathological Characteristics Included in the Discovery and Validation Cohort

Characteristics	Discovery GSE25066 (n = 488)	Validation
		All Trials (n = 553)	GSE20194 (n = 278)	GSE20271 (n = 178)	GSE22093 (n = 97)
Age
≤50	268	287	133	100	54
>50	220	264	144	78	42
Unknown	0	2	1	0	1
ER
Negative	200	249	114	80	55
Positive	287	304	164	98	42
Unknown	1	0	0	0	0
HER2
Negative	466	463	219	151	97
Positive	5	85	59	26	0
Unknown	17	1	0	1	0
cT
T0-1	29	42	26	13	3
T2	245	274	147	76	51
T3	140	113	50	37	26
T4	74	121	53	51	17
Unknown	0	3	2	1	0
cN
N0	154	159	79	59	21
N1	231	212	125	71	16
N2	64	79	31	38	10
N3	39	54	42	9	3
Unknown	0	49	1	1	47
Grade
1-2	201	225	117	76	32
3	252	271	152	72	47
Unknown	35	57	9	30	18
pCR
Yes	99	110	56	26	28
No	389	443	222	152	69

cT, clinical tumor stage; cN, clinical nodal status.