Table 1.
Treatment (dose mg/kg) | Baseline IL-6 (pg/ml) | IL-6 – 3 hr after first polyICLC injection (pg/ml) | IL-6 – 3 hr after final polyICLC injection (pg/ml) | Offspring gender | Age of offspring at sacrifice (Months) |
---|---|---|---|---|---|
Saline | 0 | 0 | 0 | Male | 41 |
Saline | 0 | 0 | 0 | Male | 41 |
Saline | 0 | 0 | 0 | Male | 43 |
Saline | 60 | 55.3 | 38.6 | Male | 46 |
PolyICLC (0.25) | 0 | 3635.0 | 324.4 | Female | 41 |
PolyICLC (0.5) | 0 | 6938.2 | 155.0 | Female | 42 |
PolyICLC (0.5) | 0 | 14302.0 | 3789.8 | Male | 46 |
PolyICLC (1.0) | 0 | 23441.0 | 1200.0 | Male | 44 |