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Minimum inhibitory concentration of RIF in combination with H2O2 as an oxidant against M. smegmatis wild-type and antibiotic resistant strains.
| Effect of combinatorial treatment of H2O2 and RIF on M. smegmatis strains | |||||
|---|---|---|---|---|---|
| MIC for H2O2 (μg/mL) | MIC for RIF (μg/mL) | MIC for combination H2O2 + RIF (μg/mL) | Fold change (RIF) | FICI | |
| M. smegmatis | |||||
| Wild-type mc2155 | 170 | 32 | 85 + 8 | 4 | 0.75 |
| Antibiotic resistant strains (Lab-selected mutants) | |||||
| Strain 1 | 170 | 64 | 85 + 8 | 8 | 0.63 |
| Strain 2 | 170 | 256 | 85 + 64 | 4 | 0.75 |
