Figure 2.

Outline of amygdala to hippocampal CA1 inputs. The basolateral amygdala nucleus (BL) is divided into anterior part (BLa) and posterior part (BLp). Both BLa and BLp project directly to ventral hippocampal CA1 (vCA1) and establish monosynaptic and glutamatergic circuits. In physiological condition, BLp–vCA1 projection is more intensive than BLa–vCA1 projection. Activation of BLa–vCA1 inputs induces anxiety and social deficits; while activation of BLp–vCA1 inputs mediates HOPE-facilitated spatial memory.