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. 2017 Oct 31;8:2143. doi: 10.3389/fmicb.2017.02143

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Copyright © 2017 Rizzo, Soffritti, D’Accolti, Bortolotti, Di Luca and Caselli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Modulation induced by HHV-6A and 6B infection on specific miRNAs associated to NK cell functions. NK-92 cells were uninfected (control) or infected with HHV-6A or 6B cell-free inocula, then analyzed at 1, 2, 3, and 6 d.p.i. for miRNA expression by individual assays detecting miRNAs already known for their role in NK cell maturation, activation of effector functions. Results are expressed as fold-change ± SD, compared to control values, and represent the mean value of duplicate samples from three independent experiments. Statistically significant values are marked with asterisks (^∗p ≤ 0.01; ^∗∗p < 0.001).