Table 4.

Motivation effects on group-dependent brain activities during reappraisal.

Region of activation	Side	BA	MNI coordinates			Cluster size	Z score
			x	y	z
A. BASD
Control > MDD
Inferior frontal gyrus	L	45	−28	34	−4		2.16
Posterior cingulate	R	23	12	−34	18		2.56
Posterior cingulate	L	29	−12	−44	18	695	2.39
Lentiform nucleus	R		22	−20	2	87	2.28
Parahippocampal gyrus	L	36	−28	−34	−10	196	2.1
Middle temporal gyrus	L	39	−40	−66	20	105	2.01
Superior temporal gyrus	L	39	−48	−54	16		1.82
B. BASR
Control > MDD
Inferior frontal gyrus	R	45	46	22	10	55	2.02
Parahippocampal gyrus	R	19	42	−46	−8		2.93
Posterior cingulate	R	30	28	−70	10	361
Anterior cingulate	R	32	14	40	14	72
C. BASF
Control > MDD
Posterior cingulate	L	29	0	−36	−20	64	2.25
Superior temporal gyrus	L	13	−50	−46	24		1.82
MDD > Control
Lentiform nucleus	L		−28	−8	−2	93	2.12
Midbrain	L		−2	−20	−4	52	2.05
Lentiform nucleus	R		30	−8	2	42	1.82
D. BIS
Control > MDD
Inferior frontal gyrus	L	45	−36	34	218		2.29
Lentiform nucleus	R		28	8	4	939	2.32

The group-by-motivation interaction identified regions where BIS/BAS scores modulated brain responses differently between the depressed patients and the control group regardless of reappraisal conditions. All clusters were thresholded at P < 0.05 and AlphaSim-corrected with an extent of at least 54 voxels.