. 2017 Oct 19;3(4):562–570. doi: 10.1016/j.trci.2017.09.003

Table 1.

Inclusion and exclusion criteria for the International Physical Activity Questionnaire study

Inclusion criteria	Exclusion criteria
• Age 60–80 years • English speaker • Adequate visual and auditory acuity to complete neuropsychological testing • Willingness to participate in entirety of study • Willingness and ability to provide written informed consent • A letter from the usual general practitioner endorsing participants ability to partake in all aspects of the study	• Dementia diagnosis or another neurodegenerative disease • Score ≤26 on the Mini–Mental State Examination • Score of ≥6 on the Geriatric Depression Scale (Short Form) • Inability to undertake cycling-based exercise due to neuromuscular and/or musculoskeletal limitations • Inability to obtain medical clearance to participate in the exercise program • History of schizophrenia, schizoaffective disorder, or bipolar disorder • Subjects with untreated obstructive sleep apnea • History of electroconvulsive therapy or serious head injury resulting in a prolonged period of unconsciousness • History of alcohol abuse or dependence within 2 years of screening • Participants with a history of cancer (other than skin or in situ prostate cancer) within the previous 5 years • Any significant systemic illness or unstable medical condition • Insulin-requiring diabetes or uncontrolled diabetes mellitus • Uncontrolled hypertension (systolic BP > 170 or diastolic BP > 100 mmHg) • Participants in whom magnetic resonance imaging is contraindicated including, but not limited to, those with a pacemaker, presence of metallic fragments near the eyes or spinal cord, or cochlear implant (dental fillings do not present a risk for magnetic resonance imaging).

Inclusion criteria

Exclusion criteria

•
Age 60–80 years
•
English speaker
•
Adequate visual and auditory acuity to complete neuropsychological testing
•
Willingness to participate in entirety of study
•
Willingness and ability to provide written informed consent
•
A letter from the usual general practitioner endorsing participants ability to partake in all aspects of the study

•
Dementia diagnosis or another neurodegenerative disease
•
Score ≤26 on the Mini–Mental State Examination
•
Score of ≥6 on the Geriatric Depression Scale (Short Form)
•
Inability to undertake cycling-based exercise due to neuromuscular and/or musculoskeletal limitations
•
Inability to obtain medical clearance to participate in the exercise program
•
History of schizophrenia, schizoaffective disorder, or bipolar disorder
•
Subjects with untreated obstructive sleep apnea
•
History of electroconvulsive therapy or serious head injury resulting in a prolonged period of unconsciousness
•
History of alcohol abuse or dependence within 2 years of screening
•
Participants with a history of cancer (other than skin or in situ prostate cancer) within the previous 5 years
•
Any significant systemic illness or unstable medical condition
•
Insulin-requiring diabetes or uncontrolled diabetes mellitus
•
Uncontrolled hypertension (systolic BP > 170 or diastolic BP > 100 mmHg)
•
Participants in whom magnetic resonance imaging is contraindicated including, but not limited to, those with a pacemaker, presence of metallic fragments near the eyes or spinal cord, or cochlear implant (dental fillings do not present a risk for magnetic resonance imaging).