Table 1. Main signals observed in the GWAS of skin pigmentation (M-values).
SNP | CHR | POS | NEA/EA | Gene | Frq EA | INFO | Betaa | SEa | Pa | Betab | SEb | Pb |
---|---|---|---|---|---|---|---|---|---|---|---|---|
rs2003589 | 2 | 217527465 | T/C | IGFBP2 | 0.063 | 0.843 | 0.885 | 0.177 | 9.54E–07 | 2.464 | 0.494 | 1.05E–06 |
rs853807 | 5 | 67752638 | C/T | 0.485 | 0.956 | −0.347 | 0.077 | 8.45E–06 | −0.961 | 0.213 | 9.75E–06 | |
rs57836066 | 6 | 71304950 | T/G | RP11-134K13.4 | 0.086 | 0.979 | −0.661 | 0.137 | 2.17E–06 | −1.838 | 0.382 | 2.40E–06 |
rs2373391 | 7 | 88449300 | T/A | ZNF804B | 0.681 | 0.987 | −0.384 | 0.083 | 4.98E–06 | −1.076 | 0.232 | 5.09E–06 |
rs7945369 | 11 | 103425586 | T/C | 0.537 | 0.968 | −0.405 | 0.079 | 5.26E–07 | −1.159 | 0.224 | 3.97E–07 |
Notes.
Beta estimate using standardized residuals.
Beta estimate using unstandardized residuals.