Table 1.

Summary for qualitative assessment of histology sections. The MI group demonstrated swelling of the PCT cells and rare hyaline casts, identified in the tubular lumen. On the other hand, the S+MI group showed PCT dilation with thinning of the epithelial lining and swelling of the cells. MI and S+MI groups showed prominent focal loss of the brush border of PCTs. A total of 10 fields were screened per slide, 5 slides per mouse and 5 mice per group. The overall assessment was denoted as (+) for mild, (++) for moderate, and (+++) for severe.

	Ctrl	S	MI	S+MI
Glomerular retraction	−	+	−	+
Interstitium
Dilation of PCTs	−	++	++	++
Interstitium
(i) Thinning of PCT lining	−	−	++	+++
(ii) Focal loss of brush border
(iii) Swelling of PCT cells
Vessels
(i) Subintimal fibrosis	−	−	−	−
(ii) Vasculitis