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. 2017 Oct 22;2017:3267352. doi: 10.1155/2017/3267352

Table 1.

Current completed phase I and II clinical trials on stem cell and ischemic stroke.

Stem cell completed clinical trials for ischemic stroke
Authors NCT Stage of trial Type of stem cells used/mode of delivery Primary outcomes Results
Kalladka et al. 2016 [9] 01151124 Phase I NSCs: CTX-DP drug product/stereotactic ipsilateral putamen injection Incidence of adverse events No adverse events were seen
NIHSS improvement ranged from 0–5 (secondary outcome)
Qiao et al. 2014 [69] NA Phase I Cotransplantation with neural stem/progenitor cells and mesenchymal stromal cells/IV Safety and feasibility No evidence of neurological deterioration or neurological infection
Prasad et al. 2014 02425670 Phase II BM mononuclear cells/IV Functional ability-modifiedBarthel Index score No significant difference between BMSC versus control in Barthel Index score
Banerjee et al. 2014 00535197 Phase I CD34+ stem cells/intra-arterial Safety Safe and feasible
Savitz and Sean 2014 00859024 Phase I Autologous mononuclear bone marrow cells/IV Adverse events No study-related adverse events

IV: intravenous; BMSC: bone marrow stem cells; NIHSS: National Institute of Health Stroke Scale; NCT: National Clinical Trial Number.