Table 2.

Histopathologic scoring of lung lesions

Rank*	Group	Mouse	Severity/ % Lung Involvement
1	Wt	4	Severe/ 50%
2	Wt	2	Severe/ 40%
3	Wt	1	Moderate/ 50%
4	Wt	5	Moderate/ 50%
5	vacJ−	2	Moderate/ 30%
6	vacJ−	4	Moderate to severe/ 20%
7	Wt	3	Moderate/ 30%
8	vacJ−	3	Moderate to severe/ 10%
9	vacJ−	5	Mild to moderate/ 15%
10	vacJ−	1	Mild/ 50%

^*Lung lesions were ranked 1–10 from most to least severe based on degree of histologically evident bacterial load, neutrophilic inflammation, tissue damage, and approximate percent of the lung involved. The lesions in the wild-type group were significantly worse than the vacJ⁻ group (p=0.036, Mann-Whitney test).