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. 2017 Nov 1;8:218. doi: 10.3389/fpsyt.2017.00218

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Copyright © 2017 Cannella, Cosa-Linan, Roscher, Takahashi, Vogler, Wängler and Spanagel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Whole brain glucose uptake in Age Control, 0crit and 3crit rats. (A) Average reconstructions of microPET scans showing [18F]-fluorodeoxyglucose (FDG) uptake in Age Control (upper row), 0crit (middle row), and 3crit (lower row) under baseline (left column) condition and cocaine (middle column) or yohimbine (right column) treatment. (B) Standardized uptake value (SUV) of the whole brain after injection of FDG in combination with saline or cocaine or yohimbine in Age Control, 0crit, and 3crit rats. ***p < 0.001 vs baseline.