Table 4. Predicting semen samples from infertile patients and from fertile donors.
| Variable | sORP (Youden's Index) | Total number (WHO cutoff) | Total motility (WHO cutoff) | Progressive motility (WHO cutoff) | Normal morphology (WHO cutoff) |
|---|---|---|---|---|---|
| Cutoff for infertility | >1.41 mV/106/mL | 39×106 | 40% | 32% | <4% |
| Sensitivity | 57.3% (52.0–62.4) | 28.2% (23.7–33.1) | 40.8% (35.7–46.1) | 88.0% (84.2–91.1) | 50.4% (45.2–55.7) |
| Specificity | 78.0% (64.0–88.5) | 92.0% (80.8–97.8) | 94.0% (83.5–98.7) | 28.0% (16.2–42.5) | 84.0% (70.9–92.8) |
| PPV | 95.0% (91.2–97.5) | 96.3% (90.7–99.0) | 98.0% (94.3–99.6) | 89.9% (86.3–92.8) | 95.8% (92.0–98.2) |
| NPV | 20.0% (14.6–26.3) | 14.9% (11.1–19.4) | 17.9% (13.4–23.0) | 24.1% (13.9–37.2) | 18.8% (13.9–24.6) |
| Accuracy | 60% | 35.9% | 47.2% | 80.7% | 54.5% |
Values are presented with 95% confidence interval.
sORP, static oxidation-reduction potential; WHO, World Health Organization; PPV, positive predictive value; NPV, negative predictive value.
Adapted from Arafa et al. Andrologia 2017 Aug 3 [58], permission of John Wiley and Sons.