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. 2017 Nov 1;8:777. doi: 10.3389/fphar.2017.00777

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Copyright © 2017 Deng, Xing, Sun, Xu, Wu, Li and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative expression of ERβ (A), PI3K (B), p-PI3K (C), Akt (D), p-Akt (E) and an internal reference (α–tubulin) (F) in MIRI-LVR rats treated with high-dose of GXDSF treated group and PHTPP. Compared with the sham group: ^##P < 0.01. Compared with the MIRI-LVR model group: ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001. Compared with the high-dose of GXDSF treated group: ^&&&P < 0.001. The data are presented as the mean ± SD (n = 6 in each group).