Table 3.

HPV11E6 and HPV18E6 shared Top 10 up- and down-regulated genes based on either the extent of up- or downregulation or on their known involvement in cellular transformation.

Up-regulated			Down-regulated
Gene symbol	Gene name	Fold change	Gene symbol	Gene name	Fold change
MIR4461	MicroRNA 4461	3.2	CEACAM 5	Carcinoembryonic antigen related cell adhesion molecule 5	−4.2
TRAJ59	T-cell receptor alpha joining 59	3.0	CYP1A1	Cytochrome P450, subfamily I	−2.6
PTHLH	Parathyroid hormone-like hormone	2.6	BCL6	B-cell CLL/lymphoma 6	−2.4
FST	Follistatin	2.6	MMP12	Matrix metalloproteinase 12	−2.3
KPNA1	Karyopherin subunit alpha 1	2.2	STOM	Stomatin	−2.3
SERPINB2	Serpin family B member 2	2.1	SNORD32B	Small nucleolar RNA, C/D box 32B	−2.3
INHBA	Inhibin beta A subunit	2.0	DMBT1	Deleted in malignant brain tumors 1	−2.2
MIR4481	MicroRNA 4481	2.0	LOXL4	Lysyl oxidase-like protein 4	−2.2
RN5S191	RNA, 5 S Ribosomal 191	2.0	DUOX2	Dual oxidase 2	−2.2
BTC	Betacellulin	2.0	CYP24A1	Cytochrome P450 family 24 subfamily a member 1	−2.0