Figure 6.

Analysis of gene expression changes in wild-type and Gsk3 DKO mESCs. A, work flow of alternative splicing (AS) and differential expression (DE) analysis from RNA-Seq. B, total number of genes differing in alternative splicing or differential expression between wild-type and DKO cells. The six genes observed in both populations are indicated below the Venn diagram. C, categories of alternative splicing for the 194 changing splicing events detected by MAJIQ. Categories are defined as indicated by the schematics, followed by number of events in that category. Events not falling in any single category are defined as “Complex.”