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The effects of AGAP and W38G on heart rate (A and D) and enzyme activities (B, C, E, and F) of CK and LDH at doses up to 2.5 and 5.0 mg/kg. In each experiment, data points represent mean ± S.E. (error bars) (n = 10 for saline and 2.5 mg/kg W38G, n = 8 for 5.0 mg/kg W38G, n = 6 for 2.5 mg/kg AGAP, n = 4 for 5.0 mg/kg AGAP). Statistically significant differences compared with the saline control group (calculated using one-way ANOVA) are indicated by p < 0.05 (*) or p < 0.01 (**).
