Figure 6.

Analgesic effects of AGAP and W38G in mice. Both AGAP and W38G have analgesic effects in rodent pain models. W38G was similarly effective as AGAP at reducing thermal-induced pain (A and B). W38G was similarly effective as AGAP in attenuating nociceptive behavior (duration of paw licking and flinching time) during phase I (0–5 min postinjection) (C) and phase II (20–40 min postinjection) (D) following intraplantar injection of formalin. Data points are shown as mean ± S.E. (error bars) (n = 10). Statistically significant differences compared with the saline control group (calculated using one-way ANOVA) are indicated by p < 0.05 (*) and p < 0.01 (**).