Table 2.

Effects of AGAP and W38G on the kinetic of hNa_v1.7 and hNa_v1.8

*, p < 0.05; significant difference between control and toxins on hNa_v1.7 and hNa_v1.8; one-way ANOVA. #, p < 0.05; significant difference between AGAP and W38G on hNa_v1.7 and hNa_v1.8; one-way ANOVA. **, p < 0.01; significant difference between control and toxins on hNa_v1.7 and hNa_v1.8; one-way ANOVA. ##, p < 0.01; significant difference between AGAP and W38G on hNa_v1.7 and hNa_v1.8; one-way ANOVA.

Group	hNav1.7			hNav1.8
	Control	AGAP (100 nm)	W38G (100 nm)	Control	AGAP (100 nm)	W38G (100 nm)
Activation
V½ (mV)	−35.38 ± 0.33	−41.35 ± 0.78*	−43.35 ± 0.95*	0.79 ± 0.55	−3.13 ± 0.75*	−4.88 ± 0.9*
k	5.11 ± 0.27	6.15 ± 0.69	5.05 ± 0.78	10.77 ± 0.5	11.39 ± 0.68	11.35 ± 0.8
Inactivation
V½ (mV)	−54.81 ± 0.98	−52.60 ± 0.82	−55.24 ± 0.70	−67.84 ± 0.63	−70.16 ± 0.56	−67.8 ± 0.48
k	9.34 ± 0.92	9.65 ± 0.77	9.33 ± 0.65	10.93 ± 0.57	10.84 ± 0.52	9.15 ± 0.44