Table 1. Presenting features of patients with CML at diagnosis and sampling.
Patient | Age | Sex | Diagnosis time (month/year) | Sampling time (month/year) | Treatment prior tosampling | Immature Neutrophils (%) | Diagnosis | Ph+ (%) | BCR-ABL1a |
---|---|---|---|---|---|---|---|---|---|
Isolation of MVs | |||||||||
1 | 32 | M | 8 / 2011 | 9 / 2011 | Noneb | 93 | CML-CPc | 98 | + |
2 | 26 | F | 8 / 2011 | 9 / 2011 | None | 91 | CML-CP | 95 | + |
3 | 14 | F | 1 / 2011 | 11 / 2011 | Hud | 90 | CML-CP | NAe | + |
4 | 19 | M | 1 / 2011 | 1 / 2012 | Hu | 97 | CML-CP | 100 | + |
5 | 32 | F | 12 / 2011 | 1 / 2012 | None | 99 | CML-CP | 100 | 0.411 |
6 | 35 | M | 12 / 2011 | 1 / 2012 | None | 93 | CML-CP | 100 | 0.451 |
7 | 42 | M | 2 / 2012 | 3 / 2012 | None | 56 | CML-CP | 78 | 0.209 |
8 | 13 | F | 3 / 2012 | 3 / 2012 | None | 94 | CML-CP | 100 | + |
9 | 45 | F | 3 / 2012 | 3 / 2012 | None | 80 | CML-CP | 100 | + |
10 | 19 | M | 2 / 2012 | 4 / 2012 | Hu | 94 | CML-CP | 100 | + |
11 | 40 | M | 3 / 2012 | 4 / 2012 | None | 99 | CML-CP | 100 | + |
Isolation of BM-MSCs | |||||||||
1 | 41 | M | 3 / 2012 | 3 / 2012 | None | 98 | CML-CP | 100 | + |
2 | 46 | F | 4 / 2012 | 4 / 2012 | None | 96 | CML-CP | 97 | + |
3 | 29 | M | 4 / 2012 | 4 / 2012 | None | 98 | CML-CP | 100 | + |
4 | 22 | F | 3 / 2017 | 3 / 2017 | None | 91 | CML-CP | 97 | 0.653 |
5 | 36 | F | 3 / 2017 | 3 / 2017 | None | 95 | CML-CP | 96 | 0.524 |
6 | 43 | M | 4 / 2017 | 4 / 2017 | None | 96 | CML-CP | 98 | 0.412 |
aBCR-ABL gene was detected for all of the patients by reverse transcription PCR (+/−) or real-time quantitative PCR.
bNone means no treatments prior to diagnosis.
cCML-CP, chronic phase of CML.
dHu stands for treatment of oral hydroxyurea.
eNo data available.