Table 1. Physiological and biochemical parameters of the acute liver failure (ALF) rats and age-matched control (CON) rats. Data are expressed as mean±SD. n=6. *P<0.05, **P<0.01 vs CON rats.
| Parameters | CON | ALF |
|---|---|---|
| Physiological parameters | ||
| Body weight (BW) (g) | 252.63±12.70 | 232.70±11.94** |
| Liver weight (% BW) | 2.99±0.42 | 4.47±0.26** |
| Serum | ||
| ALT (IU/L) | 27.39±4.15 | 250.08±47.44** |
| AST (IU/L) | 46.03±15.01 | 377.03±85.29** |
| AKP (IU/L) | 165.83±45.60 | 316.03±82.37** |
| Total bilirubin (μmol/L) | 3.39±1.25 | 6.13±2.48** |
| Conjugated bilirubin (μmol/L) | 1.59±1.48 | 4.09±2.87** |
| TNF-α(pg/mL) | 7.69±3.10 | 130.88±40.90** |
| Ammonia (μmol/L) | 76.85±18.78 | 88.53±21.33 |
| Creatinine (μmol/L) | 44.83±15.15 | 47.17±17.63 |
| Urea nitrogen (mmol/L) | 4.89±1.18 | 5.38±1.05 |
| Liver | ||
| GSH-Px (units/mg protein) | 183.97±41.75 | 122.28±24.20* |
| CAT (units/mg protein) | 25.75±7.21 | 16.62±4.43* |
| SOD (units/mg protein) | 42.66±7.46 | 41.02±6.91 |
| MDA (nmol/mg protein) | 2.87±0.72 | 4.21±0.80* |