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Histopathological photomicrographs of pancreas tissue (6100x magnification; scale bar: 20 μm). (a) Normal control rats had normal islets of Langerhans (IL). (b) The rats from the diabetic control group showed disruption of the IL with degenerative as well as necrotic changes. (c–f) Glibenclamide- and GP-treated rats showed a notable degree of protection, with markedly decreased necrosis of IL cells.
