Table 2.
The effects of GP fruit extract and glibenclamide on glucose-induced hyperglycemia in rats with STZ-induced diabetes.
| Groups | Blood glucose level (mg/dL) | ||||
|---|---|---|---|---|---|
| 0 h | 1 h | 2 h | 3 h | 4 h | |
| Normal Control | 110.31 ± 4.05# | 115.12 ± 4.17# | 113.32 ± 3.21 | 111.00 ± 6.41# | 110.72 ± 5.46# |
| Diabetic Control | 335.43 ± 19.05 | 353.46 ± 21.11 | 359.00 ± 16.30 | 351.4 ± 19.44 | 347.80 ± 27.81 |
| Diabetic + Glibenclamide | 421.90 ± 36.08 | 456.40 ± 45.18∗ | 385.40 ± 45.18∗ | 356.00 ± 16.48∗ | 334.68 ± 20.45∗ |
| Diabetic + GP (250 mg/kg) | 435.20 ± 38.07 | 467.40 ± 31.31∗ | 435.40 ± 39.52 | 415.20 ± 26.20 | 407.84 ± 32.38 |
| Diabetic + GP (500 mg/kg) | 343.80 ± 18.50 | 374.60 ± 29.56∗ | 359.50 ± 21.48 | 335.20 ± 9.45 | 325.30 ± 8.30 |
| Diabetic + GP (1000 mg/kg) | 320.80 ± 15.23 | 351.60 ± 12.09∗ | 324.40 ± 18.72∗ | 304.40 ± 35.43∗ | 276.48 ± 24.82∗ |
Data are represented as the mean ± SD (n = 6). ∗ denotes a significant difference (p < 0.05) between the treatment groups and the diabetic control group; # denotes a significant difference (p < 0.05) when the normal control group was compared to the diabetic control group. The comparisons were made by one-way ANOVA followed by Dunnett's multiple comparison test.