Table 1.
Effect of treatment with Withania somnifera (WS) on SK-N-SH cell survival after 24 h with Aβ peptide (50 µg/ml) using lactate dehydrogenase (LDH) and XTT assays†
(Mean values with their standard errors of four or five separate experiments performed in triplicate at least in each group)
Aβ (50 µg/ml) + WS (μg/ml) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Control | Aβ (50 μg/ml) | WS-0·5 | WS-1·0 | WS-5·0 | ||||||
Assay | Mean | sem | Mean | sem | Mean | sem | Mean | sem | Mean | sem |
LDH | 100·0** | 3·61 | 134·32 | 6·32 | 122·11 | 4·10 | 114·25** | 3·79 | 109·28** | 2·80 |
XTT | 100·0** | 4·98 | 42·31 | 6·08 | 62·17 | 7·32 | 69·03 | 13·75 | 71·87* | 4·03 |
Mean value was significantly different from that of the Aβ group: * P < 0·05, ** P < 0·01.
† Results are expressed as percentage of control (taken as 100 %).