Table 1.
mUPDRS Ratings, 0–3 |
||
---|---|---|
Motor Symptoms | Subject J (n = 15)* | Subject K (n = 25)* |
Axiala | 2.0 (0.1) | 2.3 (0.1) |
Rigidity | 1.0 (0.3) | 2.1 (0.2) |
Tremor | 0.0 (0.0) | 0.3 (0.1) |
Bradykinesia | 1.8 (0.1) | 2.4 (0.4) |
Akinesia | 1.8 (0.2) | 2.5 (0.3) |
Food retrieval | 1.5 (0.3) | 2.5 (0.3) |
Total (≤18) | 8.2 | 12.1 |
Values are means (SD). mUPDRS, modified Unified Parkinson’s Disease Rating Scale. mUPDRS for nonhuman primates was used to assess motor symptoms in each animal, rating axial motor symptoms (gait, posture, balance) as well as upper and lower limb rigidity, bradykinesia, akinesia, and tremor (on the side contralateral to neural recordings) using a 0–3 scale (0 = normal, 3 = severe; maximum total score of 18).
axial symptoms are an average of posture, gait, and balance scores;
n = no. of observations, except for axial scores, which are n = 4 and 5 for subjects J and K, respectively.