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. 2017 Nov 6;4(5):ENEURO.0316-17.2017. doi: 10.1523/ENEURO.0316-17.2017

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Copyright © 2017 Lau et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — GBP treatment or α2δ-1 deletion decreases FL-driven synaptogenesis. A, MIPs from of three optical sections of confocal images of VGlut1 (green) and PSD95 (red) collected at 100× from Layer V of WT and α2δ-1^−/− (KO) FL and sham-injured animals, with vehicle or GBP treatment. White arrow indicates colocalization of VGLUT1 and PSD95, representing a site of synaptic contact. Scale bar = 500 nm. B, Box-whisker plot of number of synapses (colocalization of VGlut1/PSD95) per 1.00 mm³ per MIP, **α = 0.01 and ***α = 0.001 (Holm-Bonferroni multiple-comparison correction).