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. Author manuscript; available in PMC: 2017 Nov 6.
Published in final edited form as: Biochem Pharmacol. 2016 Jun 14;113:88–96. doi: 10.1016/j.bcp.2016.06.007

Table 1.

In silico prediction of microRNAs targeting 3′-UTR of CYP2B6.

# miRNAs Position Binding free energies (kcal/mol)
1 hsa-miR-92a 1068 −30.90
2 hsa-miR-128a-3p 397 −29.00
3 hsa-miR-504-5pa 17 −28.40
4 hsa-miR-92b-3p 1068 −26.90
5 hsa-miR-25-3pa 1068 −26.70
6 hsa-miR-485-5p 745 −26.10
7 hsa-miR-367-3p 1072 −26.00
8 hsa-miR-363-3p 1072 −24.90
9 hsa-miR-7-5p 1374 −24.40
10 hsa-miR-134-5p 1356 −24.30
11 hsa-miR-148b-3p 1466 −22.90
12 hsa-miR-148a-3p 1466 −22.90
13 hsa-miR-152-3p 1467 −22.10
14 hsa-miR-421 1314 −21.60
15 hsa-miR-542-3p 664/898 −20.80/−21.90
16 hsa-miR-216a-5p 161 −20.40
17 hsa-miR-216b-5p 1113 −20.40
18 hsa-miR-185 865 −19.20
19 hsa-miR-129b 1472 −19.10
20 hsa-miR-32 1072 −18.90
21 hsa-miR-141 1254 −17.90
22 hsa-miR-200a 1254 −17.50
23 hsa-miR-143 928 −16.90
24 hsa-miR-29a 1473 −16.40
25 hsa-miR-29c 1473 −16.20
26 hsa-miR-590-3p 521/549/569 −13.60/−14.50/−13.70
27 hsa-miR-590-5p 524 −12.60
28 hsa-miR-374b 174 −7.80
29 hsa-miR-21 525 −5.90
a

The correlations (r) between CYP2B6 RNA levels and hsa-miR-504-5p, or and hsa-miR-25-3p expression in normal liver tissues were −0.405 or −0.359, respectively.