Table 2.
Cosinor analysis of circadian clock rhythmicity in human BMSCs, ADSCs, and DPSCs following dexamethasone synchronisation.
| Cell | Gene | Period (h) | p value | Acrophase (°) | Amplitude | Mesor | Robustness (%) |
|---|---|---|---|---|---|---|---|
| BMSC | Bmal1∗ | 23.9 | 0.007 | −76 | 0.331 | 0.451 | 76.2 |
| Per2 | 20.2 | 0.076 | −261 | 1.099 | 1.597 | 52.1 | |
| Rev-erbA | 26.0 | 0.391 | −287 | 1.853 | 3.158 | 23.6 | |
| ADSC | Bmal1∗ | 20.0 | 0.006 | −289 | 1.264 | 1.885 | 77.4 |
| Per2∗ | 23.4 | 0.021 | −98 | 0.502 | 0.486 | 66.6 | |
| Rev-erbA∗ | 21.8 | 0.001 | −314 | 0.611 | 0.914 | 85.1 | |
| DPSC | Bmal1 | 20.0 | 0.571 | −9 | 0.325 | 0.720 | 14.9 |
| Per2 | 26.0 | 0.101 | −176 | 1.089 | 1.071 | 47.9 | |
| Rev-erbA | 26.0 | 0.055 | −266 | 4.952 | 4.938 | 56.2 |
∗Significance according to the cosinor analysis software.