Table 1. Monitoring of clinical parameters during the study.

End point	Baseline ( n  = 937)	Month 1 ( n  = 821)	Month 3 ( n  = 743)	Month 6 ( n  = 698)	Month 9 ( n  = 137)	Month 12 ( n  = 106)
Pain at rest (VAS score)	55.9 ± 11.4	31.8 ± 9.7	24.9 ± 10.2	24.1 ± 9.1	25.3 ± 7.3	25.9 ± 6.9
Pain on movement (VAS score)	72.1 ± 9.8	48.3 ± 6.7	38.2 ± 7.7	37.9 ± 7.3	38.4 ± 6.5	38.9 ± 11.5
WOMAC score	56.8 ± 8.7	45.7 ± 7.9	27.6 ± 10.3	24.8 ± 8.8	N/A	N/A.
Acetaminophen/NSAIDs use	48.8%	27.4%	19.4%	19.6%	N/A	N/A
Patient satisfaction
Worsening (%)		2.4	3.2	4.8
Unchanged (%)		9.3	8.9	9.6
Improved (%)		88.3	87.9	85.6

Abbreviations: N/A, not available; NSAID, nonsteroidal anti-inflammatory drug; VAS, visual analog scale; WOMAC, Western Ontario McMasters University Osteoarthritis Index.