Table 2.
Multivariate analysis for disease-free and overall survival
| Covariate | Overall survival |
Disease-free survival
|
||
|---|---|---|---|---|
| HR (95% CI) | P-Value | HR (95% CI) | P-Value | |
| Treatment arm | ||||
| SD-R | 1 | 0.439 | 1 | 0.242 |
| HD-R | 0.81 (0.48 – 1.38) | 0.74 (0.45 – 1.23) | ||
|
| ||||
| Age in years | ||||
| < 65 | 1 | 0.076 | 1 | 0.199 |
| ≥ 65 | 1.60 (0.95 – 2.68) | 1.38 (0.84 – 2.25) | ||
|
| ||||
| Disease status before translant | ||||
| CR/CRu | 1 | 0.032 | 1 | 0.024 |
| PR/SD | 1.79 (1.05 – 3.06) | 1.79 (1.08 – 2.95) | ||
|
| ||||
| No. of prior lines of treatmnet | ||||
| ≤ 2 | 1 | 0.002 | 1 | 0.016 |
| > 2 | 2.30 (1.34 – 3.94) | 1.89 (1.13 – 3.18) | ||
Abbreviations: CR/CRu, complete remission/complete remission unconfirmed; HR, hazard ratio; HD-R, high-dose rituximab; No., number; PR/SD, partial response/stable disease; SD-R, standard-dose rituximab.