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. 2016 Dec 9;60(3):585–596. doi: 10.1007/s00125-016-4159-1

Fig. 3.

Fig. 3

Generation and characterisation of Shp-1-Tg mice. (a) Schema of LSL-Shp-1 mice crossbred with Sm22α-CreKI mice to generate mice overexpressing ShP-1 specifically in VSMCs. (b–e) SHP-1 mRNA and protein from aortas and aortic SMCs from control and Shp-1-Tg mice; n = 3–5. Tg, Shp-1-Tg mice. *p < 0.05, **p < 0.01 and ***p < 0.001 for indicated comparison